Advanced Infertility: Male

Empiric Medical Therapy of Male Subfertility

When an infertile man presents for evaluation, but no specific abnormalities are found to account for this problem, then the patient has idiopathic infertility. It is predictable that patients would expect a medical therapy to improve sperm production or quality, given the number and varieties of treatment that are now available for various medical problems. In my experience, patients frequently request, and are surprised by, the paucity of effective nonspecific medical treatments for male infertility.
http://www.maleinfertility.org/new-therapy.html

Men’s Health and Fertility Lifestyle Information

http://www.maleinfertility.org/lifestyle.html

Y Chromosome Infertility

Disease characteristics. Y chromosome infertility is characterized by azoospermia (absence of sperm), severe oligozoospermia (<1 x 106 sperm/mL semen), moderate oligozoospermia (1-5 x 106 sperm/mL semen), or mild oligozoospermia (5-20 x 106 sperm/mL semen). Males with Y chromosome infertility usually have no obvious symptoms, although physical examination may reveal small testes and/or cryptorchidism.
http://www.genetests.org/servlet/access?db=geneclinics&site=gt&id=8888892&key=WjVURBazPL4YF&gry=&fcn

Spermatogenic Failure, Nonobstructive, Y-Linked

Azoospermia, Nonobstructive, Y-Linked Oligozoospermia, Nonobstructive, Y-Linked Oligospermia, Nonobstructive, Y-Linked Spermatogenic Arrest, Y-Linked Azoospermia Factor Regions, Included AZF Regions, Included
http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=415000

Y Deletion and Infertility

http://genesanddrugs.dnadirect.com/patients/tests/infertility/more_about/yDeletion_inf.jsp

Y chromosome Inside Infertility

Deletions in the Y chromosome can lead to infertility. Mark Jobling is turning to fertile men to find out why such deletions occur.
http://genome.wellcome.ac.uk/doc_wtd020834.html

Genetic Abnormalities and Testing Y chromosome (AZF) microdeletions

Center for Male Reproductive Medicine and Microsurgery
http://www.maleinfertility.org/new-noa.html#azf

Y chromosome (AZF ) microdeletions

The diagnosis of azoospermia is often associated with a genetic etiology. For men with congenital absence of the vas deferens, 60% will have a detectable cystic fibrosis gene mutation 10. The female partner should also be tested to see if she is a carrier. If both partners are carriers, the risk of having a child affected by crystic fibrosis is 50%. Up to 17% or more men with NOA will have detectable genetic abnormalities that will only become apparent with the rudimentary tests of Y-chromosome partial deletion analysis and karyotype testing.
http://www.maleinfertility.org/new-retrieval4.html#genetic

Klinefelter's Syndrome

(47, XXY) Wikipedia
http://en.wikipedia.org/wiki/Klinefelter's_syndrome

Klinefelter Syndrome

Genetics Home Reference
http://ghr.nlm.nih.gov/condition=klinefeltersyndrome

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	Advanced Infertility: Male Empiric Medical Therapy of Male Subfertility When an infertile man presents for evaluation, but no specific abnormalities are found to account for this problem, then the patient has idiopathic infertility. It is predictable that patients would expect a medical therapy to improve sperm production or quality, given the number and varieties of treatment that are now available for various medical problems. In my experience, patients frequently request, and are surprised by, the paucity of effective nonspecific medical treatments for male infertility. http://www.maleinfertility.org/new-therapy.html Men’s Health and Fertility Lifestyle Information http://www.maleinfertility.org/lifestyle.html Y Chromosome Infertility Disease characteristics. Y chromosome infertility is characterized by azoospermia (absence of sperm), severe oligozoospermia (<1 x 106 sperm/mL semen), moderate oligozoospermia (1-5 x 106 sperm/mL semen), or mild oligozoospermia (5-20 x 106 sperm/mL semen). Males with Y chromosome infertility usually have no obvious symptoms, although physical examination may reveal small testes and/or cryptorchidism. http://www.genetests.org/servlet/access?db=geneclinics&site=gt&id=8888892&key=WjVURBazPL4YF&gry=&fcn Spermatogenic Failure, Nonobstructive, Y-Linked Azoospermia, Nonobstructive, Y-Linked Oligozoospermia, Nonobstructive, Y-Linked Oligospermia, Nonobstructive, Y-Linked Spermatogenic Arrest, Y-Linked Azoospermia Factor Regions, Included AZF Regions, Included http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=415000 Y Deletion and Infertility http://genesanddrugs.dnadirect.com/patients/tests/infertility/more_about/yDeletion_inf.jsp Y chromosome Inside Infertility Deletions in the Y chromosome can lead to infertility. Mark Jobling is turning to fertile men to find out why such deletions occur. http://genome.wellcome.ac.uk/doc_wtd020834.html Genetic Abnormalities and Testing Y chromosome (AZF) microdeletions Center for Male Reproductive Medicine and Microsurgery http://www.maleinfertility.org/new-noa.html#azf Y chromosome (AZF ) microdeletions The diagnosis of azoospermia is often associated with a genetic etiology. For men with congenital absence of the vas deferens, 60% will have a detectable cystic fibrosis gene mutation 10. The female partner should also be tested to see if she is a carrier. If both partners are carriers, the risk of having a child affected by crystic fibrosis is 50%. Up to 17% or more men with NOA will have detectable genetic abnormalities that will only become apparent with the rudimentary tests of Y-chromosome partial deletion analysis and karyotype testing. http://www.maleinfertility.org/new-retrieval4.html#genetic Klinefelter's Syndrome (47, XXY) Wikipedia http://en.wikipedia.org/wiki/Klinefelter's_syndrome Klinefelter Syndrome Genetics Home Reference http://ghr.nlm.nih.gov/condition=klinefeltersyndrome Previous Page \| Next Page